A mutant vesicular stomatitis virus with reduced cytotoxicity and enhanced anterograde trans-synaptic efficiency

A mutant vesicular stomatitis virus with reduced cytotoxicity and enhanced anterograde trans-synaptic efficiency

Abstract Understanding the connecting structure of brain network is the basis to reveal the principle of the brain function and elucidate the mechanism of brain diseases. Trans-synaptic tracing with neurotropic viruses has become one of the most effective technologies to dissect the neural circuits....

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Bibliographic Details
Main Authors: Kunzhang Lin, Xin Zhong, Min Ying, Lei Li, Sijue Tao, Xutao Zhu, Xiaobin He, Fuqiang Xu
Format: Article
Language:English
Published: BMC 2020-03-01
Series:Molecular Brain
Subjects:
Neurotropic virus
Output network tracing
Vesicular stomatitis virus
Attenuated cytotoxicity
Enhanced anterograde trans-synaptic tracing
Online Access:http://link.springer.com/article/10.1186/s13041-020-00588-3

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http://link.springer.com/article/10.1186/s13041-020-00588-3

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