Exacerbation of CNS inflammation and neurodegeneration by systemic LPS treatment is independent of circulating IL-1β and IL-6

<p>Abstract</p> <p>Background</p> <p>Chronic neurodegeneration comprises an inflammatory response but its contribution to the progression of disease remains unclear. We have previously shown that microglial cells are primed by chronic neurodegeneration, induced by the M...

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Bibliographic Details
Main Authors: Cunningham Colm, Skelly Donal T, Murray Carol L
Format: Article
Language:English
Published: BMC 2011-05-01
Series:Journal of Neuroinflammation
Subjects:
Online Access:http://www.jneuroinflammation.com/content/8/1/50