Conventional colon adenomas harbor various disturbances in microsatellite stability and contain micro-serrated foci with microsatellite instability.

INTRODUCTION:Colorectal cancer belongs to the most frequent occurring malignancies. A prediction of the clinical outcome and appropriate choice of neoadjuvant chemotherapy needs personalized insight to the main driving pathways. Because most CRCs have polyps as progenitor lesions, studying the pathw...

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Main Authors: Piotr Lewitowicz, Stanislaw Gluszek, Dorota Koziel, Agata Horecka-Lewitowicz, Magdalena Chrapek, Przemyslaw Wolak, Justyna Klusek, Anna Nasierowska-Guttmejer
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5325232?pdf=render