Lycopene mitigates acrylamide and glycidamide induced cellular toxicity via oxidative stress modulation in HepG2 cells

Lycopene mitigates acrylamide and glycidamide induced cellular toxicity via oxidative stress modulation in HepG2 cells

Acrylamide (ACR), a carcinogen and neurotoxin formed in carbohydrate-rich high temperature processed foods, undergo epoxidation in cells to form more toxic metabolite glycidamide (GLY). The present study investigated antioxidant potential of lycopene (LYC) against ACR and GLY induced toxicity in hum...

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Bibliographic Details
Main Authors: T.R. Reshmitha, P. Nisha
Format: Article
Language:English
Published: Elsevier 2021-05-01
Series:Journal of Functional Foods
Subjects:
Acrylamide
Glycidamide
Antioxidants
Free radicals
Oxidative damage
Lycopene
Online Access:http://www.sciencedirect.com/science/article/pii/S1756464621000396

Internet

http://www.sciencedirect.com/science/article/pii/S1756464621000396

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