LC-MS/MS quantification of sulfotransferases is better than conventional immunogenic methods in determining human liver SULT activities: implication in precision medicine

LC-MS/MS quantification of sulfotransferases is better than conventional immunogenic methods in determining human liver SULT activities: implication in precision medicine

Abstract This study aims to determine whether enzyme activities are correlated with protein amounts and mRNA expression levels of five major human sulfotransferase (SULT) enzymes in 10 matched pericarcinomatous and hepatocellular carcinoma liver samples. The MRM UHPLC-MS/MS method, Western blot and...

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Bibliographic Details
Main Authors: Cong Xie, Tong-meng Yan, Jia-mei Chen, Xiao-yan Li, Juan Zou, Li-jun Zhu, Lin-lin Lu, Ying Wang, Fu-yuan Zhou, Zhong-qiu Liu, Ming Hu
Format: Article
Language:English
Published: Nature Publishing Group 2017-06-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-017-04202-w

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https://doi.org/10.1038/s41598-017-04202-w

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