Experimental infection with the hookworm, Necator americanus, is associated with stable gut microbial diversity in human volunteers with relapsing multiple sclerosis

Experimental infection with the hookworm, Necator americanus, is associated with stable gut microbial diversity in human volunteers with relapsing multiple sclerosis

Abstract Background Helminth-associated changes in gut microbiota composition have been hypothesised to contribute to the immune-suppressive properties of parasitic worms. Multiple sclerosis is an immune-mediated autoimmune disease of the central nervous system whose pathophysiology has been linked...

Full description

Bibliographic Details
Main Authors: Timothy P. Jenkins, David I. Pritchard, Radu Tanasescu, Gary Telford, Marina Papaiakovou, Riccardo Scotti, Alba Cortés, Cris S. Constantinescu, Cinzia Cantacessi
Format: Article
Language:English
Published: BMC 2021-04-01
Series:BMC Biology
Subjects:
Relapsing multiple sclerosis
Hookworm
Helminth therapy
Bacterial 16S rRNA sequencing
Bacterial richness
Bacterial diversity
Online Access:https://doi.org/10.1186/s12915-021-01003-6

Internet

https://doi.org/10.1186/s12915-021-01003-6

Similar Items