Staufen1 Interacts with Multiple Components of the Ebola Virus Ribonucleoprotein and Enhances Viral RNA Synthesis

Staufen1 Interacts with Multiple Components of the Ebola Virus Ribonucleoprotein and Enhances Viral RNA Synthesis

Ebola virus (EBOV) is a negative-strand RNA virus with significant public health importance. Currently, no therapeutics are available for Ebola, which imposes an urgent need for a better understanding of EBOV biology. Here we dissected the virus-host interplay between EBOV and host RNA-binding prote...

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Bibliographic Details
Main Authors: Jingru Fang, Colette Pietzsch, Palaniappan Ramanathan, Rodrigo I. Santos, Philipp A. Ilinykh, Mariano A. Garcia-Blanco, Alexander Bukreyev, Shelton S. Bradrick
Format: Article
Language:English
Published: American Society for Microbiology 2018-10-01
Series:mBio
Subjects:
RNA binding proteins
RNA replication
ebola virus
virus-host interactions
Online Access:https://doi.org/10.1128/mBio.01771-18

Internet

https://doi.org/10.1128/mBio.01771-18

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