Sphingosine 1-phosphate activation of ERM contributes to vascular calcification[S]

Vascular calcification is the deposition of mineral in the artery wall by vascular smooth muscle cells (VSMCs) in response to pathological stimuli. The process is similar to bone formation and is an independent risk factor for cardiovascular disease. Given that ceramide and sphingosine 1-phosphate (...

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Bibliographic Details
Main Authors: Thomas G. Morris, Samantha J. Borland, Christopher J. Clarke, Claire Wilson, Yusuf A. Hannun, Vasken Ohanian, Ann E. Canfield, Jacqueline Ohanian
Format: Article
Language:English
Published: Elsevier 2018-01-01
Series:Journal of Lipid Research
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S002222752033933X