Improvement in detecting cytomegalovirus drug resistance mutations in solid organ transplant recipients with suspected resistance using next generation sequencing.

Improvement in detecting cytomegalovirus drug resistance mutations in solid organ transplant recipients with suspected resistance using next generation sequencing.

<h4>Objetives</h4>The aim of this study was to identify CMV drug resistance mutations (DRM) in solid organ transplant (SOT) recipients with suspected resistance comparing next-generation sequencing (NGS) with Sanger sequencing and assessing risk factors and the clinical impact of resista...

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Main Authors: Rubén López-Aladid, Alba Guiu, Maria Mar Mosquera, Francisco López-Medrano, Frederic Cofán, Laura Linares, Julián Torre-Cisneros, Elisa Vidal, Asunción Moreno, Jose María Aguado, Elisa Cordero, Cecilia Martin-Gandul, Jordi Carratalá, Nuria Sabé, Jordi Niubó, Carlos Cervera, Alicia Capón, Anna Cervilla, Marta Santos, Marta Bodro, Patricia Muñoz, Maria Carmen Fariñas, Andrés Antón, Maitane Aranzamendi, Miguel Montejo, Pilar Pérez-Romero, Oscar Len, Maria Ángeles Marcos
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0219701

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https://doi.org/10.1371/journal.pone.0219701

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