Seronegative Neuromyelitis Optica Spectrum - The challenges on disease definition and pathogenesis

Seronegative Neuromyelitis Optica Spectrum - The challenges on disease definition and pathogenesis

Neuromyelitis optica spectrum disorders (NMOSD) are characterized by severe optic neuritis and/or longitudinally extensive transverse myelitis, and some brain lesions are also unique to NMOSD. Serum autoantibodies against aquaporin-4 (AQP4) are detected in most cases of NMOSD. However, some patients...

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Bibliographic Details
Main Authors: Douglas Kazutoshi Sato, Dagoberto Callegaro, Marco Aurélio Lana-Peixoto, Ichiro Nakashima, Kazuo Fujihara
Format: Article
Language:English
Published: Academia Brasileira de Neurologia (ABNEURO) 2014-06-01
Series:Arquivos de Neuro-Psiquiatria
Subjects:
neuromielite óptica
aquaporina-4
glicoproteína associada ao olidendrócito
mielite
neurite óptica
diagnóstico diferencial
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2014000600445&lng=en&tlng=en

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2014000600445&lng=en&tlng=en

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