The Aromatic Head Group of Spider Toxin Polyamines Influences Toxicity to Cancer Cells

The Aromatic Head Group of Spider Toxin Polyamines Influences Toxicity to Cancer Cells

Spider venoms constitute incredibly diverse libraries of compounds, many of which are involved in prey capture and defence. Polyamines are often prevalent in the venom and target ionotropic glutamate receptors. Here we show that a novel spider polyamine, PA366, containing a hydroxyphenyl-based struc...

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Bibliographic Details
Main Authors: David Wilson, Glen M. Boyle, Lachlan McIntyre, Matthew J. Nolan, Peter G. Parsons, Jennifer J. Smith, Leon Tribolet, Alex Loukas, Michael J. Liddell, Lachlan D. Rash, Norelle L. Daly
Format: Article
Language:English
Published: MDPI AG 2017-10-01
Series:Toxins
Subjects:
spider venom
NMR spectroscopy
polyamine
cancer
cytotoxicity
Online Access:https://www.mdpi.com/2072-6651/9/11/346

Internet

https://www.mdpi.com/2072-6651/9/11/346

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