Telomerase Induction in HPV Infection and Oncogenesis

Telomerase extends the repetitive DNA at the ends of linear chromosomes, and it is normally active in stem cells. When expressed in somatic diploid cells, it can lead to cellular immortalization. Human papillomaviruses (HPVs) are associated with and high-risk for cancer activate telomerase through t...

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Bibliographic Details
Main Author: Rachel Katzenellenbogen
Format: Article
Language:English
Published: MDPI AG 2017-07-01
Series:Viruses
Subjects:
Online Access:https://www.mdpi.com/1999-4915/9/7/180