Cellular source of hypothalamic macrophage accumulation in diet-induced obesity

Cellular source of hypothalamic macrophage accumulation in diet-induced obesity

Abstract Background Obese mice on a high-fat diet (HFD) display signs of inflammation in the hypothalamic arcuate nucleus (ARC), a critical area for controlling systemic energy metabolism. This has been suggested as a key mechanism of obesity-associated hypothalamic dysfunction. We reported earlier...

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Bibliographic Details
Main Authors: Chan Hee Lee, Sung Hoon Shin, Gil Myoung Kang, Seongjun Kim, Jiye Kim, Rina Yu, Min-Seon Kim
Format: Article
Language:English
Published: BMC 2019-11-01
Series:Journal of Neuroinflammation
Subjects:
Obesity
Hypothalamus
Inflammation
Macrophages
Development
Online Access:http://link.springer.com/article/10.1186/s12974-019-1607-0

Internet

http://link.springer.com/article/10.1186/s12974-019-1607-0

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