Mitochondrial localized STAT3 is involved in NGF induced neurite outgrowth.

BACKGROUND: Signal transducer and activator of transcription 3 (STAT3) plays critical roles in neural development and is increasingly recognized as a major mediator of injury response in the nervous system. Cytokines and growth factors are known to phosphorylate STAT3 at tyrosine(705) with or withou...

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Bibliographic Details
Main Authors: Lihan Zhou, Heng-Phon Too
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3124549?pdf=render