Comprehensive Identification of Immunodominant Proteins of Brucella abortus and Brucella melitensis Using Antibodies in the Sera from Naturally Infected Hosts

Comprehensive Identification of Immunodominant Proteins of Brucella abortus and Brucella melitensis Using Antibodies in the Sera from Naturally Infected Hosts

Brucellosis is a debilitating zoonotic disease that affects humans and animals. The diagnosis of brucellosis is challenging, as accurate species level identification is not possible with any of the currently available serology-based diagnostic methods. The present study aimed at identifying Brucella...

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Bibliographic Details
Main Authors: Gamal Wareth, Murat Eravci, Christoph Weise, Uwe Roesler, Falk Melzer, Lisa D. Sprague, Heinrich Neubauer, Jayaseelan Murugaiyan
Format: Article
Language:English
Published: MDPI AG 2016-04-01
Series:International Journal of Molecular Sciences
Subjects:
Brucella
host specificity
mass spectrometry
Liquid chromatography–mass spectrometry (LC-MS)
two dimensional electrophoresis
2D-PAGE
Matrix-assisted laser desorption/ionization-Tine of Flight-Mass Spectrometry MALDI-TOF MS
proteomics
Western blot
Online Access:http://www.mdpi.com/1422-0067/17/5/659

Internet

http://www.mdpi.com/1422-0067/17/5/659

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