The dimeric Golgi protein Gorab binds to Sas6 as a monomer to mediate centriole duplication

The dimeric Golgi protein Gorab binds to Sas6 as a monomer to mediate centriole duplication

The duplication and ninefold symmetry of the Drosophila centriole requires that the cartwheel molecule, Sas6, physically associates with Gorab, a trans-Golgi component. How Gorab achieves these disparate associations is unclear. Here, we use hydrogen–deuterium exchange mass spectrometry to define Go...

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Bibliographic Details
Main Authors: Agnieszka Fatalska, Emma Stepinac, Magdalena Richter, Levente Kovacs, Zbigniew Pietras, Martin Puchinger, Gang Dong, Michal Dadlez, David M Glover
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2021-03-01
Series:eLife
Subjects:
Gorab
Sas6
centriole duplication
Rab6
Golgi
Online Access:https://elifesciences.org/articles/57241

Internet

https://elifesciences.org/articles/57241

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