Overexpression of arginine transporter CAT-1 is associated with accumulation of L-arginine and cell growth in human colorectal cancer tissue.

Overexpression of arginine transporter CAT-1 is associated with accumulation of L-arginine and cell growth in human colorectal cancer tissue.

We previously showed that L-arginine (Arg) accumulates in colorectal cancer tissues. The aim of this study was to investigate the mechanism by which Arg accumulates and determine its biological significance. The concentration of Arg and Citrulline (Cit) in sera and tumor tissues from colorectal canc...

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Bibliographic Details
Main Authors: Ying Lu, Weimin Wang, Junchen Wang, Chunzhang Yang, Huiming Mao, Xuelian Fu, Yanling Wu, Jingping Cai, Junyi Han, Zengguang Xu, Zhengping Zhuang, Zhongmin Liu, Hai Hu, Bingguan Chen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3765253?pdf=render

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http://europepmc.org/articles/PMC3765253?pdf=render

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