D-pinitol Inhibits Prostate Cancer Metastasis through Inhibition of αVβ3 Integrin by Modulating FAK, c-Src and NF-κB Pathways

D-pinitol Inhibits Prostate Cancer Metastasis through Inhibition of αVβ3 Integrin by Modulating FAK, c-Src and NF-κB Pathways

Prostate cancer is the most commonly diagnosed malignancy in men and shows a predilection for metastasis to the bone. D-pinitol, a 3-methoxy analogue of d-chiro-inositol, was identified as an active principle in soy foods and legumes, and it has been proven to induce tumor apoptosis and metastasis o...

Full description

Bibliographic Details
Main Authors: Chih-Hsin Tang, Wen-Chi Chen, Hsin-Ho Liu, Shang-Sen Lee, Teng-Fu Hsieh, Chi-Cheng Chen, Tsung-Hsun Tsai, Tien-Huang Lin, Tzu-Wei Tan
Format: Article
Language:English
Published: MDPI AG 2013-05-01
Series:International Journal of Molecular Sciences
Subjects:
D-pinitol
integrin
prostate cancer
migration
FAK
Online Access:http://www.mdpi.com/1422-0067/14/5/9790

Internet

http://www.mdpi.com/1422-0067/14/5/9790

Similar Items