Interferon and biologic signatures in dermatomyositis skin: specificity and heterogeneity across diseases.

BACKGROUND: Dermatomyositis (DM) is an autoimmune disease that mainly affects the skin, muscle, and lung. The pathogenesis of skin inflammation in DM is not well understood. METHODOLOGY AND FINDINGS: We analyzed genome-wide expression data in DM skin and compared them to those from healthy controls....

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Bibliographic Details
Main Authors: David Wong, Bory Kea, Rob Pesich, Brandon W Higgs, Wei Zhu, Patrick Brown, Yihong Yao, David Fiorentino
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3250414?pdf=render