AAV-Txnip prolongs cone survival and vision in mouse models of retinitis pigmentosa

AAV-Txnip prolongs cone survival and vision in mouse models of retinitis pigmentosa

Retinitis pigmentosa (RP) is an inherited retinal disease affecting >20 million people worldwide. Loss of daylight vision typically occurs due to the dysfunction/loss of cone photoreceptors, the cell type that initiates our color and high-acuity vision. Currently, there is no effective treatm...

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Bibliographic Details
Main Authors: Yunlu Xue, Sean K Wang, Parimal Rana, Emma R West, Christin M Hong, Helian Feng, David M Wu, Constance L Cepko
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2021-04-01
Series:eLife
Subjects:
retina
neurodegeneration
gene therapy
cone photoreceptor
retinal metabolism
mitochondria
Online Access:https://elifesciences.org/articles/66240

Internet

https://elifesciences.org/articles/66240

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