Exosomes Secreted by Adipose-Derived Mesenchymal Stem Cells Foster Metastasis and Osteosarcoma Proliferation by Increasing COLGALT2 Expression

Exosomes Secreted by Adipose-Derived Mesenchymal Stem Cells Foster Metastasis and Osteosarcoma Proliferation by Increasing COLGALT2 Expression

ObjectivesHomosapien collagen beta (1-O) galactosyl transferase 2 (COLGALT2) is an important enzyme during collagen glycosylation, yet its biological functions in cancer are incompletely understood. Our previous study revealed that in the osteosarcoma microenvironment, adipose-derived mesenchymal st...

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Bibliographic Details
Main Authors: Yan Wang, Yijing Chu, Kun Li, Guoqing Zhang, Zhu Guo, Xiaolin Wu, Chensheng Qiu, Yan Li, Xin Wan, Jing Sui, Dan Zhang, Hongfei Xiang, Bohua Chen
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-05-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
exosomes
adipose-derived mesenchymal stem cells
osteosarcoma
Homo sapiens collagen beta (1-O)galactosyltransferase 2
metastasis
Online Access:https://www.frontiersin.org/article/10.3389/fcell.2020.00353/full

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https://www.frontiersin.org/article/10.3389/fcell.2020.00353/full

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