Histone Acetylation Promotes Neutrophil Extracellular Trap Formation

Histone Acetylation Promotes Neutrophil Extracellular Trap Formation

Neutrophils undergo a unique form of cell death to generate neutrophil extracellular traps (NETs). It is well established that citrullination of histones (e.g., CitH3) facilitates chromatin decondensation during NET formation (NETosis), particularly during calcium-induced NETosis that is independent...

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Bibliographic Details
Main Authors: Hussein J. Hamam, Meraj A. Khan, Nades Palaniyar
Format: Article
Language:English
Published: MDPI AG 2019-01-01
Series:Biomolecules
Subjects:
neutrophils
NETosis
histone acetylation
histone decondensation
histone deacetylase inhibitors
Online Access:http://www.mdpi.com/2218-273X/9/1/32

Internet

http://www.mdpi.com/2218-273X/9/1/32

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