Long Non-coding RNAs Rian and Miat Mediate Myofibroblast Formation in Kidney Fibrosis

Long Non-coding RNAs Rian and Miat Mediate Myofibroblast Formation in Kidney Fibrosis

There is an increasing prevalence of chronic kidney disease (CKD), which associates with the development of interstitial fibrosis. Pericytes (perivascular fibroblasts) provide a major source of α-SMA-positive myofibroblasts that are responsible for the excessive deposition of extracellular matrix. I...

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Bibliographic Details
Main Authors: Roel Bijkerk, Yu Wah Au, Wendy Stam, Jacques M. G. J. Duijs, Angela Koudijs, Ellen Lievers, Ton J. Rabelink, Anton Jan van Zonneveld
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-03-01
Series:Frontiers in Pharmacology
Subjects:
long non-coding RNA
kidney fibrosis
myofibroblast
pericyte
Miat
Rian
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2019.00215/full

Internet

https://www.frontiersin.org/article/10.3389/fphar.2019.00215/full

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