Successful human infection with P. falciparum using three aseptic Anopheles stephensi mosquitoes: a new model for controlled human malaria infection.

Successful human infection with P. falciparum using three aseptic Anopheles stephensi mosquitoes: a new model for controlled human malaria infection.

Controlled human malaria infection (CHMI) is a powerful method for assessing the efficacy of anti-malaria vaccines and drugs targeting pre-erythrocytic and erythrocytic stages of the parasite. CHMI has heretofore required the bites of 5 Plasmodium falciparum (Pf) sporozoite (SPZ)-infected mosquitoes...

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Bibliographic Details
Main Authors: Matthew B Laurens, Peter Billingsley, Adam Richman, Abraham G Eappen, Matthew Adams, Tao Li, Sumana Chakravarty, Anusha Gunasekera, Christopher G Jacob, B Kim Lee Sim, Robert Edelman, Christopher V Plowe, Stephen L Hoffman, Kirsten E Lyke
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3712927?pdf=render

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http://europepmc.org/articles/PMC3712927?pdf=render

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