Downregulation of protein kinase CK2 activity facilitates tumor necrosis factor-α-mediated chondrocyte death through apoptosis and autophagy.

Downregulation of protein kinase CK2 activity facilitates tumor necrosis factor-α-mediated chondrocyte death through apoptosis and autophagy.

Despite the numerous studies of protein kinase CK2, little progress has been made in understanding its function in chondrocyte death. Our previous study first demonstrated that CK2 is involved in apoptosis of rat articular chondrocytes. Recent studies have suggested that CK2 downregulation is associ...

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Bibliographic Details
Main Authors: Sung Won Lee, Yeon Suk Song, Sang Yeob Lee, Young Geol Yoon, Sang Hwa Lee, Bong Soo Park, Il Yun, Hyantae Choi, Kunhong Kim, Won Tae Chung, Young Hyun Yoo
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3084779?pdf=render

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http://europepmc.org/articles/PMC3084779?pdf=render

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