Protective Antibodies against Placental Malaria and Poor Outcomes during Pregnancy, Benin

Protective Antibodies against Placental Malaria and Poor Outcomes during Pregnancy, Benin

Placental malaria is caused by Plasmodium falciparum–infected erythrocytes that bind to placental tissue. Binding is mediated by VAR2CSA, a parasite antigen coded by the var gene, which interacts with chondroitin sulfate A (CSA). Consequences include maternal anemia and fetal growth retardation. Ant...

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Bibliographic Details
Main Authors: Nicaise Tuikue Ndam, Lise Denoeud-Ndam, Justin Doritchamou, Firmine Viwami, Ali Salanti, Morten A. Nielsen, Nadine Fievet, Achille Massougbodji, Adrian J.F. Luty, Philippe Deloron
Format: Article
Language:English
Published: Centers for Disease Control and Prevention 2015-05-01
Series:Emerging Infectious Diseases
Subjects:
Plasmodium falciparum
parasites
malaria
placental malaria
variant surface antigen 2 chondroitin sulfate
VAR2CSA
Online Access:https://wwwnc.cdc.gov/eid/article/21/5/14-1626_article

Internet

https://wwwnc.cdc.gov/eid/article/21/5/14-1626_article

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