Bone Marrow Transfer in Relapsing-Remitting EAE Ameliorates Disease at First Remission, with No Synergistic Effect upon Co-Transplantation with Mesenchymal Stem Cells

Bone Marrow Transfer in Relapsing-Remitting EAE Ameliorates Disease at First Remission, with No Synergistic Effect upon Co-Transplantation with Mesenchymal Stem Cells

Multiple sclerosis (MS) is a neurological disorder characterized by an autoimmune response, demyelinating plaques and axonal damage. Intense immunosuppression (II) followed by autologous hematopoietic stem cell transplantation has been proposed as a treatment in severe forms of MS. We have used muri...

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Bibliographic Details
Main Authors: Giovanni Ferrara, Federico Ivaldi, Gianluigi Mancardi, Nicole Kerlero de Rosbo, Antonio Uccelli
Format: Article
Language:English
Published: MDPI AG 2021-07-01
Series:Vaccines
Subjects:
stem cell therapy
multiple sclerosis
intensive immunosuppression
experimental autoimmune encephalomyelitis
bone-marrow cells
mesenchymal stem cells
Online Access:https://www.mdpi.com/2076-393X/9/7/736

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https://www.mdpi.com/2076-393X/9/7/736

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