Regulation of TGFβ Signalling by TRPV4 in Chondrocytes

The growth factor TGFβ and the mechanosensitive calcium-permeable cation channel TRPV4 are both important for the development and maintenance of many tissues. Although TRPV4 and TGFβ both affect core cellular functions, how their signals are integrated is unknown. Here we show that pharmacological a...

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Bibliographic Details
Main Authors: Steven Woods, Paul A. Humphreys, Nicola Bates, Sophie Alice Richardson, Shweta Yogesh Kuba, Imogen R. Brooks, Stuart A. Cain, Susan J. Kimber
Format: Article
Language:English
Published: MDPI AG 2021-03-01
Series:Cells
Subjects:
Online Access:https://www.mdpi.com/2073-4409/10/4/726