Bone morphogenetic protein-2 functions as a negative regulator in the differentiation of myoblasts, but not as an inducer for the formations of cartilage and bone in mouse embryonic tongue

<p>Abstract</p> <p>Background</p> <p>In vitro studies using the myogenic cell line C2C12 demonstrate that bone morphogenetic protein-2 (BMP-2) converts the developmental pathway of C2C12 from a myogenic cell lineage to an osteoblastic cell lineage. Further, in vivo stud...

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Bibliographic Details
Main Authors: Suzuki Erika, Suga Takeo, Yamane Akira, Aoyama Kayoko, Fukui Tadayoshi, Nakamura Yoshiki
Format: Article
Language:English
Published: BMC 2011-07-01
Series:BMC Developmental Biology
Online Access:http://www.biomedcentral.com/1471-213X/11/44