Monoclonal therapy against calcitonin gene-related peptide lowers hyperglycemia and adiposity in type 2 diabetes mouse models

Monoclonal therapy against calcitonin gene-related peptide lowers hyperglycemia and adiposity in type 2 diabetes mouse models

Objective: Calcitonin Gene-Related Peptide α (CGRPα) is a multifunctional neuropeptide found in the central and peripheral nervous system with cardiovascular, nociceptive, and gastrointestinal activities. CGRPα has been linked to obesity and insulin secretion but the role of this circulating peptide...

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Bibliographic Details
Main Authors: Jonathan Halloran, Alexandre Lalande, Mandy Zang, Harshita Chodavarapu, Céline E. Riera
Format: Article
Language:English
Published: Elsevier 2020-12-01
Series:Metabolism Open
Subjects:
CGRP
Neuropeptide
Obesity
Diabetes
Insulin secretion
Hyperglycemia
Online Access:http://www.sciencedirect.com/science/article/pii/S2589936820300402

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http://www.sciencedirect.com/science/article/pii/S2589936820300402

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