Serum Corticosterone and Insulin Resistance as Early Biomarkers in the hAPP23 Overexpressing Mouse Model of Alzheimer’s Disease

Serum Corticosterone and Insulin Resistance as Early Biomarkers in the hAPP23 Overexpressing Mouse Model of Alzheimer’s Disease

Increasing epidemiological evidence highlights the association between systemic insulin resistance and Alzheimer’s disease (AD). As insulin resistance can be caused by high-stress hormone levels and since hypercortisolism appears to be an important risk factor of AD, we aimed to investigate the syst...

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Bibliographic Details
Main Authors: Jhana O. Hendrickx, Sofie De Moudt, Elke Calus, Wim Martinet, Pieter-Jan D. F. Guns, Lynn Roth, Peter P. De Deyn, Debby Van Dam, Guido R. Y. De Meyer
Format: Article
Language:English
Published: MDPI AG 2021-06-01
Series:International Journal of Molecular Sciences
Subjects:
hypercortisolism
insulin resistance
hypermetabolism
cognitive decline
Alzheimer’s disease
Online Access:https://www.mdpi.com/1422-0067/22/13/6656

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https://www.mdpi.com/1422-0067/22/13/6656

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