Staphylococcal β-Toxin Modulates Human Aortic Endothelial Cell and Platelet Function through Sphingomyelinase and Biofilm Ligase Activities

Staphylococcus aureus causes many infections, such as skin and soft tissue, pneumonia, osteomyelitis, and infective endocarditis (IE). IE is an endovascular infection of native and prosthetic valves and the lining of the heart; it is characterized by the formation of cauliflower-like “vegetations” c...

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Bibliographic Details
Main Authors: Alfa Herrera, Katarina Kulhankova, Vijay K. Sonkar, Sanjana Dayal, Aloysius J. Klingelhutz, Wilmara Salgado-Pabón, Patrick M. Schlievert, Eric A. Johnson
Format: Article
Language:English
Published: American Society for Microbiology 2017-03-01
Series:mBio
Online Access:http://mbio.asm.org/cgi/content/full/8/2/e00273-17