eIF4E/Fmr1 double mutant mice display cognitive impairment in addition to ASD-like behaviors

eIF4E/Fmr1 double mutant mice display cognitive impairment in addition to ASD-like behaviors

Autism spectrum disorder (ASD) is a group of heritable disorders with complex and unclear etiology. Classic ASD symptoms include social interaction and communication deficits as well as restricted, repetitive behaviors. In addition, ASD is often comorbid with intellectual disability. Fragile X syndr...

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Bibliographic Details
Main Authors: Thu N. Huynh, Manan Shah, So Yeon Koo, Kirsten S. Faraud, Emanuela Santini, Eric Klann
Format: Article
Language:English
Published: Elsevier 2015-11-01
Series:Neurobiology of Disease
Subjects:
Autism spectrum disorders
Protein synthesis
eIF4E
Fragile X syndrome
Cognition
Genetic models
Online Access:http://www.sciencedirect.com/science/article/pii/S096999611530036X

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http://www.sciencedirect.com/science/article/pii/S096999611530036X

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