Allele-specific methylation in the FADS genomic region in DNA from human saliva, CD4+ cells, and total leukocytes

Allele-specific methylation in the FADS genomic region in DNA from human saliva, CD4+ cells, and total leukocytes

Abstract Background Genetic variants within the fatty acid desaturase (FADS) gene cluster (human Chr11) are important regulators of long-chain (LC) polyunsaturated fatty acid (PUFA) biosynthesis in the liver and consequently have been associated with circulating LC-PUFA levels. More recently, epigen...

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Bibliographic Details
Main Authors: Elaheh Rahbar, Charlotte Mae K. Waits, Edward H. Kirby, Leslie R. Miller, Hannah C. Ainsworth, Tao Cui, Susan Sergeant, Timothy D. Howard, Carl D. Langefeld, Floyd H. Chilton
Format: Article
Language:English
Published: BMC 2018-04-01
Series:Clinical Epigenetics
Subjects:
CD4+
Saliva
Leukocytes
Whole blood
Omega-6
PUFA
Online Access:http://link.springer.com/article/10.1186/s13148-018-0480-5

Internet

http://link.springer.com/article/10.1186/s13148-018-0480-5

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