Long noncoding RNA PVT1 modulates hepatocellular carcinoma cell proliferation and apoptosis by recruiting EZH2

Abstract Background We aimed to figure out the molecular network of PVT1 and EZH2 on hepatocellular carcinoma (HCC) cells growth. We also explored the interaction between PVT1, EZH2, MDM2 and P53. Methods Microarray analysis was performed to screen for abnormally expressed genes in HCC tissues and P...

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Bibliographic Details
Main Authors: Jianping Guo, Chong Hao, Congcong Wang, Luo Li
Format: Article
Language:English
Published: BMC 2018-07-01
Series:Cancer Cell International
Subjects:
P53
Online Access:http://link.springer.com/article/10.1186/s12935-018-0582-3