KR-31466, a Benzopyranylindol Analog, Attenuates Hypoxic Injury Through Mitochondrial KATP Channel and Protein Kinase C Activation in Heart-Derived H9c2 Cells

In the present study, we investigated whether a novel benzopyranylindol analogue, KR-31466 (KR466) (1-[(2S,3R,4S)-3,4-dihydro-2-dimethoxymethyl-3-hydroxy-2-methyl-6-nitro-2H-1-benzopyran-4-yl]-1H-indole-2-carboxylic acid ethyl ester) can attenuate hypoxic injury in heart-derived H9c2 cells and, if s...

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Bibliographic Details
Main Authors: Yi-Sook Jung, Yoon Seok Jung, Mi-Young Kim, Min Hwa Kim, Sunkyung Lee, Kyu Yang Yi, Sung Eun Yoo, Soo Hwan Lee, Eun Joo Baik, Chang-Hyun Moon, Joon Pil Cho
Format: Article
Language:English
Published: Elsevier 2003-01-01
Series:Journal of Pharmacological Sciences
Online Access:http://www.sciencedirect.com/science/article/pii/S1347861319326908