PlexinA2 Forward Signaling through Rap1 GTPases Regulates Dentate Gyrus Development and Schizophrenia-like Behaviors

PlexinA2 Forward Signaling through Rap1 GTPases Regulates Dentate Gyrus Development and Schizophrenia-like Behaviors

Summary: Dentate gyrus (DG) development requires specification of granule cell (GC) progenitors in the hippocampal neuroepithelium, as well as their proliferation and migration into the primordial DG. We identify the Plexin family members Plxna2 and Plxna4 as important regulators of DG development....

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Bibliographic Details
Main Authors: Xiao-Feng Zhao, Rafi Kohen, Rachel Parent, Yuntao Duan, Grace L. Fisher, Matthew J. Korn, Lingchao Ji, Guoqiang Wan, Jing Jin, Andreas W. Püschel, David F. Dolan, Jack M. Parent, Gabriel Corfas, Geoffrey G. Murphy, Roman J. Giger
Format: Article
Language:English
Published: Elsevier 2018-01-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124717318685

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http://www.sciencedirect.com/science/article/pii/S2211124717318685

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