An abundant tissue macrophage population in the adult murine heart with a distinct alternatively-activated macrophage profile.

Cardiac tissue macrophages (cTMs) are a previously uncharacterised cell type that we have identified and characterise here as an abundant GFP(+) population within the adult Cx(3)cr1(GFP/+) knock-in mouse heart. They comprise the predominant myeloid cell population in the myocardium, and are found th...

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Bibliographic Details
Main Authors: Alexander R Pinto, Rosa Paolicelli, Ekaterina Salimova, Janko Gospocic, Esfir Slonimsky, Daniel Bilbao-Cortes, James W Godwin, Nadia A Rosenthal
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/22590615/pdf/?tool=EBI