Improving Chromatin-Interaction Prediction Using Single-Cell Open-Chromatin Profiles and Making Insight Into the Cis-Regulatory Landscape of the Human Brain

Improving Chromatin-Interaction Prediction Using Single-Cell Open-Chromatin Profiles and Making Insight Into the Cis-Regulatory Landscape of the Human Brain

Single-cell open-chromatin profiles have the potential to reveal the pattern of chromatin-interaction in a cell type. However, currently available cis-regulatory network prediction methods using single-cell open-chromatin profiles focus more on local chromatin interactions despite the fact that long...

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Bibliographic Details
Main Authors: Neetesh Pandey, Omkar Chandra, Shreya Mishra, Vibhor Kumar
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-10-01
Series:Frontiers in Genetics
Subjects:
chromatin-interaction
single-cell epigenome
single-cell ATAC-seq
GWAS target
long-range
brain cis-interaction
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2021.738194/full

Internet

https://www.frontiersin.org/articles/10.3389/fgene.2021.738194/full

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