Safety Evaluation of Nano-Liposomal Formulation of Amphotericin B (SinaAmpholeish) in Animal Model as a Candidate for Treatment of Cutaneous Leishmaniasis

Safety Evaluation of Nano-Liposomal Formulation of Amphotericin B (SinaAmpholeish) in Animal Model as a Candidate for Treatment of Cutaneous Leishmaniasis

Background: Development of a topical treatment for cutaneous leishmaniasis (CL) is an important step in the im­provement of lesion management. Amphotericin B (AmB) is effective against Leishmania species but it is toxic, a Nano-liposomal form of AmB with a size of about 100nm (Lip-AmB) was develope...

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Bibliographic Details
Main Authors: Seyed Ebrahim Eskandari, Alireza Firooz, Mansour Nassiri-Kashani, Mahmoud Reza Jaafari, Amir Javadi, Akram Miramin-Mohammadi, Hossein Valian-Keshavarz, Ali Khamesipour
Format: Article
Language:English
Published: Tehran University of Medical Sciences 2018-07-01
Series:Journal of Arthropod-Borne Diseases
Subjects:
Cutaneous leishmaniasis
Nano-liposomes
Amphotericin B
Draize test
Online Access:https://jad.tums.ac.ir/index.php/jad/article/view/943

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https://jad.tums.ac.ir/index.php/jad/article/view/943

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