Enhanced anti-tumor immunotherapy by dissolving microneedle patch loaded ovalbumin.

The skin is a very suitable organ for the induction of immune responses to vaccine antigens. Antigen delivery systems to the skin by needle and syringe directly deposit the antigen into the epidermal-dermal compartment, one of the most immunocompetent sites due to the presence of professional antige...

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Bibliographic Details
Main Authors: Sung-Ju Lee, Hyeon-Seong Lee, Yun-Ho Hwang, Jong-Jin Kim, Kyung-Yun Kang, Seong Jin Kim, Hong Kee Kim, Jung Dong Kim, Do Hyeon Jeong, Man-Jeong Paik, Sung-Tae Yee
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0220382