Reassessment of the capacity of the HIV-1 Env cytoplasmic domain to trigger NF-κB activation

Reassessment of the capacity of the HIV-1 Env cytoplasmic domain to trigger NF-κB activation

Abstract The cytoplasmic domain of lentiviral Envelopes (EnvCD) ensures Env incorporation into nascent virions and regulates Env trafficking to and from the plasma membrane. It has also been reported to promote transcription from the viral LTR both directly and indirectly. Noticeably, the HIV-1 and...

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Bibliographic Details
Main Authors: Cyprien Beraud, Morgane Lemaire, Danielle Perez Bercoff
Format: Article
Language:English
Published: BMC 2018-02-01
Series:Virology Journal
Subjects:
HIV-1
Env cytoplasmic domain
NF-κB
Transcription
Online Access:http://link.springer.com/article/10.1186/s12985-018-0941-7

Internet

http://link.springer.com/article/10.1186/s12985-018-0941-7

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