Dual small-molecule targeting of SMAD signaling stimulates human induced pluripotent stem cells toward neural lineages.

Dual small-molecule targeting of SMAD signaling stimulates human induced pluripotent stem cells toward neural lineages.

Incurable neurological disorders such as Parkinson's disease (PD), Huntington's disease (HD), and Alzheimer's disease (AD) are very common and can be life-threatening because of their progressive disease symptoms with limited treatment options. To provide an alternative renewable cell...

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Bibliographic Details
Main Authors: Methichit Wattanapanitch, Nuttha Klincumhom, Porntip Potirat, Rattaya Amornpisutt, Chanchao Lorthongpanich, Yaowalak U-pratya, Chuti Laowtammathron, Pakpoom Kheolamai, Niphon Poungvarin, Surapol Issaragrisil
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4160199?pdf=render

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http://europepmc.org/articles/PMC4160199?pdf=render

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