Systematic evaluation of scoring methods for Ki67 as a surrogate for 21-gene recurrence score

Abstract Although Ki67 labeling index is a potential predictive marker for chemotherapy benefit, its clinical utility has been limited by the lack of a standard scoring method resulting in poor interobserver reproducibility. Especially, there is no consensus on the use of average versus hotspot scor...

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Bibliographic Details
Main Authors: Soonmyung Paik, Youngmee Kwon, Moo Hyun Lee, Ji Ye Kim, Da Kyung Lee, Won Jeong Cho, Eun Young Lee, Eun Sook Lee
Format: Article
Language:English
Published: Nature Publishing Group 2021-02-01
Series:npj Breast Cancer
Online Access:https://doi.org/10.1038/s41523-021-00221-z