Systematic evaluation of scoring methods for Ki67 as a surrogate for 21-gene recurrence score
Abstract Although Ki67 labeling index is a potential predictive marker for chemotherapy benefit, its clinical utility has been limited by the lack of a standard scoring method resulting in poor interobserver reproducibility. Especially, there is no consensus on the use of average versus hotspot scor...
Main Authors: | Soonmyung Paik, Youngmee Kwon, Moo Hyun Lee, Ji Ye Kim, Da Kyung Lee, Won Jeong Cho, Eun Young Lee, Eun Sook Lee |
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Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2021-02-01
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Series: | npj Breast Cancer |
Online Access: | https://doi.org/10.1038/s41523-021-00221-z |
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