Inbreeding estimates in human populations: Applying new approaches to an admixed Brazilian isolate.

The analysis of genomic data (~400,000 autosomal SNPs) enabled the reliable estimation of inbreeding levels in a sample of 541 individuals sampled from a highly admixed Brazilian population isolate (an African-derived quilombo in the State of São Paulo). To achieve this, different methods were appli...

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Bibliographic Details
Main Authors: Renan B Lemes, Kelly Nunes, Juliana E P Carnavalli, Lilian Kimura, Regina C Mingroni-Netto, Diogo Meyer, Paulo A Otto
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5916862?pdf=render