Validation of FRET Assay for the Screening of Growth Inhibitors of Escherichia coli Reveals Elongasome Assembly Dynamics

The increase in antibiotic resistant bacteria demands the development of new antibiotics against preferably new targets. The common approach is to test compounds for their ability to kill bacteria or to design molecules that inhibit essential protein activities in vitro. In the first case, the mode...

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Bibliographic Details
Main Authors: René van der Ploeg, Spyridon Theodoros Goudelis, Tanneke den Blaauwen
Format: Article
Language:English
Published: MDPI AG 2015-07-01
Series:International Journal of Molecular Sciences
Subjects:
A22
Online Access:http://www.mdpi.com/1422-0067/16/8/17637