Pyrosequencing dried blood spots reveals differences in HIV drug resistance between treatment naïve and experienced patients.

Pyrosequencing dried blood spots reveals differences in HIV drug resistance between treatment naïve and experienced patients.

Dried blood spots (DBS) are an alternative specimen collection format for HIV-1 genotyping. DBS produce HIV genotyping results that are robust and equivalent to plasma when using conventional sequencing methods. However, using tagged, pooled pyrosequencing, we demonstrate that concordance between pl...

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Bibliographic Details
Main Authors: Hezhao Ji, Yang Li, Binhua Liang, Richard Pilon, Paul MacPherson, Michèle Bergeron, John Kim, Morag Graham, Gary Van Domselaar, Paul Sandstrom, James Brooks
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3567018?pdf=render

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http://europepmc.org/articles/PMC3567018?pdf=render

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