Control of Treg cell homeostasis and immune equilibrium by Lkb1 in dendritic cells

Control of Treg cell homeostasis and immune equilibrium by Lkb1 in dendritic cells

Regulatory T (Treg) cells are important for maintaining immune homeostasis by suppressing immune cell activation, but how the Treg cell pool is maintained is still unclear. Here the authors show that a kinase, Lkb1, operates in dendritic cells (DC) to inhibit Treg cell expansion and immunosuppressio...

Full description

Bibliographic Details
Main Authors: Song Chen, Lijun Fang, Wei Guo, Yushan Zhou, Gang Yu, Wenwen Li, Kui Dong, Jingru Liu, Yuechen Luo, Bing Wang, Zhonglong Li, Chunxiao Zhao, Zhina Sun, Yue Shen, Qibing Leng, Dongming Zhou, Zhongchao Han, Huifang Huang, He Ren, Guogang Xu, Xiaoming Feng
Format: Article
Language:English
Published: Nature Publishing Group 2018-12-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-018-07545-8

Internet

https://doi.org/10.1038/s41467-018-07545-8

Similar Items