Memory B cell antibodies to HIV-1 gp140 cloned from individuals infected with clade A and B viruses.

Understanding the antibody response to HIV-1 in humans that show broad neutralizing serologic activity is a crucial step in trying to reproduce such responses by vaccination. Investigating antibodies with cross clade reactivity is particularly important as these antibodies may target conserved epito...

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Bibliographic Details
Main Authors: Hugo Mouquet, Florian Klein, Johannes F Scheid, Malte Warncke, John Pietzsch, Thiago Y K Oliveira, Klara Velinzon, Michael S Seaman, Michel C Nussenzweig
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3169578?pdf=render